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proteín promyelocytovej leukémie s motívom zinkového prstu

  1. Subject h.proteín promyelocytovej leukémie s motívom zinkového prstu
    Subject h.Promyelocytic Leukemia Zinc Finger Protein
    Entry termsproteín promyelocytickej leukémie obsahujúci motív zinkového prstu
    PLZF proteín
    ZBTB16 proteín
    proteín 16 obsahujúci zinkový prst a BTB doménu
    Scope note in EnglishA Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.
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Number of the records: 1  

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