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inhibítor rastového proteínu 1

  1. Subject h.inhibítor rastového proteínu 1
    Subject h.Inhibitor of Growth Protein 1
    Entry termsING-1 proteín
    p33ING proteín
    Scope note in EnglishA nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
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