Number of the records: 1
AIRE proteín
Subject h. AIRE proteín Subject h. AIRE Protein Entry terms APECED proteín
proteín autoimunitnej polyendokrinopatie, kandidózy a ektodermálnej dystrofie
regulátor autoimunitný, proteínEnglish X references APECED Protein
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Protein
Autoimmune Regulator ProteinScope note in English A transcriptional regulator primarily expressed in medullary thymic epithelial cells. It plays an important role in immunity by regulating the expression of a wide array of SELF-ANTIGENS and negative selection of autoreactive T-cells in the thymus. Deficiency in this protein induces a rare autosomal-recessive disease called AUTOIMMUNE POLYENDOCRINOPATHY-CANDIDIASIS-ECTODERMAL DYSTROPHY. 
subject heading
Number of the records: 1