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cisplatina

  1. Subject h.cisplatina
    Subject h.Cisplatin
    Entry termsdiaminodichlorid platiny
    cis-diaminodichlorid platiny
    cis-diamíndichlórplatina(II)
    cis-dichlórdiamínplatina(II)
    English X referencesPlatinum Diamminodichloride
    cis-Diamminedichloroplatinum(II)
    cis-Dichlorodiammineplatinum(II)
    Scope note in EnglishAn inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
    Pharmacology effect antineoplastiká
    činidlá sieťovacie
    rádiosenzibilizátory
    Pharmacology effect Antineoplastic Agents
    Cross-Linking Reagents
    Radiation-Sensitizing Agents
    Links (148) - ARTICLES
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    (22) - BOOKS
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Number of the records: 1  

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