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disulfiram

  1. Subject h.disulfiram
    Subject h.Disulfiram
    English X referencesTetraethylthiuram Disulfide
    Scope note in EnglishA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
    Pharmacology effect inhibítory acetaldehyddehydrogenázy
    prípravky na odvykanie od alkoholu
    Pharmacology effect Acetaldehyde Dehydrogenase Inhibitors
    Alcohol Deterrents
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