glioblastóm multiformný glioblastoma multiforme astrocytóm, IV. stupeň zrelosti astrocytóm, IV. stupeň diferenciácie glioblastóm obrovskobunkový
English X references
Astrocytoma, Grade IV Giant Cell Glioblastoma Glioblastoma Multiforme
Scope note in English
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
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