proteínkináza závislá od vápnika a fosfolipidov kináza závislá od vápnikom aktivovaných fosfolipidov PKC serín-treonínkináza
English X references
Calcium Phospholipid-Dependent Protein Kinase Calcium-Activated Phospholipid-Dependent Kinase PKC Serine-Threonine Kinase
Scope note in English
An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
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