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2',5'-oligoadenylátsyntetáza

  1. Subject h.2',5'-oligoadenylátsyntetáza
    Subject h.2',5'-Oligoadenylate Synthetase
    Entry terms2',5'-oligoadenylátpolymeráza
    2-5A syntetáza
    English X references2',5'-Oligoadenylate Polymerase
    2-5A Synthetase
    Scope note in EnglishAn enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.
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