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neprilyzín

  1. Subject h.neprilyzín
    Subject h.Neprilysin
    Entry termsmetaloendopeptidáza membránová
    antigény CD10
    antigény akútnej lymfoblastovej leukémie
    antigény akútnej lymfoblastickej leukémie
    endopeptidáza-24.11
    enkefalíndipeptidylkarboxypeptidáza
    enkefalináza
    proteináza kefkového lemu obličiek, neutrálna
    antigén cALLA
    English X referencesAntigens, CD10
    Antigens, Leukemia, Common Acute Lymphoblastic
    CALLA Antigen
    CD10 Antigens
    Common Acute Lymphoblastic Leukemia Antigens
    Endopeptidase-24.11
    Enkephalin Dipeptidyl Carboxypeptidase
    Enkephalinase
    Kidney-Brush-Border Neutral Proteinase
    Membrane Metallo-Endopeptidase
    Scope note in EnglishEnzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA Antigen), an important marker in the diagnosis of human acute lymphocytic leukemia. There is no relationship with CALLA PLANT.
    Links (43) - ARTICLES
    (3) - CiBaMed
    (3) - BOOKS
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