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keratodermia palmoplantárna difúzna

  1. Subject h.keratodermia palmoplantárna difúzna
    Subject h.Keratoderma, Palmoplantar, Diffuse
    Entry termsUnnov-Thostov syndróm
    keratosis palmaris et plantaris diffusa Unna-Thost
    ichthyosis palmoplantaris hereditaria
    Thostov-Unnov syndróm
    tylóza
    English X referencesThost-Unna Syndrome
    Tylosis
    Unna-Thost Syndrome
    Scope note in EnglishAn autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (KERATODERMA, PALMOPLANTAR), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present.
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