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receptory N-metyl-D-aspartátové

  1. Subject h.receptory N-metyl-D-aspartátové
    Subject h.Receptors, N-Methyl-D-Aspartate
    Entry termsreceptor N-metyl-D-aspartátový
    NMDA receptory
    receptor NMDA
    receptory NMDA
    komplex receptor NMDA-ionofór
    English X referencesN-Methyl-D-Aspartate Receptor
    N-Methyl-D-Aspartate Receptors
    NMDA Receptor
    NMDA Receptor-Ionophore Complex
    NMDA Receptors
    Receptors, NMDA
    Scope note in EnglishA class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
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    (1) - MeSH descriptor
    (5) - CiBaMed
    (5) - BOOKS
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Number of the records: 1  

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