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receptory arylhydrokarbónové

  1. Subject h.receptory arylhydrokarbónové
    Subject h.Receptors, Aryl Hydrocarbon
    Entry termsreceptory AH
    receptory pre arylhydrokarbóny
    receptory aryluhľovodíkové
    receptory dioxínové
    receptory pre dioxíny
    receptory TCDD
    receptory pre TCDD
    English X referencesAH Receptors
    Aryl Hydrocarbon Receptors
    Dioxin Receptors
    Receptors, AH
    Receptors, Dioxin
    TCDD Receptors
    Scope note in EnglishCytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
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