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syndróm poruchy adhézie leukocytov

  1. Subject h.syndróm poruchy adhézie leukocytov
    Subject h.Leukocyte-Adhesion Deficiency Syndrome
    Entry termsLAD syndróm
    Scope note in EnglishRare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
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