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proteín 1 viažuci inzulínu podobný rastový faktor

  1. Subject h.proteín 1 viažuci inzulínu podobný rastový faktor
    Subject h.Insulin-Like Growth Factor Binding Protein 1
    Entry termsproteín 1 viažuci rastový faktor podobný inzulínu
    IGF-viažuci proteín 1
    proteín 1 viažuci IGF
    IGFBP-1
    English X referencesIGF-Binding Protein 1
    IGFBP-1
    Scope note in EnglishOne of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
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