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footprinting DNA

  1. Subject h.footprinting DNA
    Subject h.DNA Footprinting
    Entry termsmapovanie DNA
    footprinty DNA
    English X referencesFootprints, DNA
    Scope note in EnglishA method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
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