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proteíny protoonkogénové c-kit

  1. Subject h.proteíny protoonkogénové c-kit
    Subject h.Proto-Oncogene Proteins c-kit
    Entry termsproteín protoonkogénový kit
    antigény CD117
    SCFR
    proteín c-kit
    p145(c-kit)
    receptor pre rastový faktor kmeňových buniek
    receptor c-kit
    English X referencesAntigens, CD117
    CD117 Antigens
    Receptor, Stem Cell Factor
    Stem Cell Factor Receptor
    c-kit Protein
    c-kit Receptor
    kit Proto-Oncogene Protein
    p145(c-kit)
    Scope note in EnglishA protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.
    See also reference (FX) in Slovak piebaldizmus
    See also reference (FX) in English Piebaldism
    Links (18) - ARTICLES
    (1) - MeSH descriptor
    (5) - CiBaMed
    (1) - BOOKS
    subject heading

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Number of the records: 1  

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