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myasthenia gravis, autoimunitná experimentálna
Subject h. myasthenia gravis, autoimunitná experimentálna Subject h. Myasthenia Gravis, Autoimmune, Experimental Entry terms myasténia gravis, autoimunitná experimentálna, pasívny prenos English X references Myasthenia Gravis, Experimental Autoimmune
Passive Transfer Experimental Autoimmune Myasthenia GravisScope note in English Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3) subject heading
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