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proteín EWS viažuci sa na RNA

  1. Subject h.proteín EWS viažuci sa na RNA
    Subject h.RNA-Binding Protein EWS
    Scope note in EnglishA ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.
    See also reference (FX) in Slovak motívy zinkových prstov
    See also reference (FX) in English Zinc Fingers
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