pre-miRNA pri-miRNA mikroRNA primárna kyseliny mikroribonukleové RNA malá temporálna miRNA stRNA
English X references
RNA, Small Temporal Small Temporal RNA miRNA stRNA
Scope note in English
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
See also reference (FX) in Slovak
RNA malá interferujúca
See also reference (FX) in English
RNA, Small Interfering
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