A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.
See also reference (FX) in Slovak
syndróm autoimunitný lymfoproliferatívny
See also reference (FX) in English
Autoimmune Lymphoproliferative Syndrome
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(1) - MeSH descriptor
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openseadragon
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