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presenilíny
Subject h. presenilíny Subject h. Presenilins Scope note in English Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years. 
subject heading
Number of the records: 1