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proteíny inzulínového receptorového substrátu

  1. Subject h.proteíny inzulínového receptorového substrátu
    Subject h.Insulin Receptor Substrate Proteins
    Entry termsproteíny substrátu inzulínového receptora
    IRS signálne adaptorové proteíny
    substrát inzulínový receptorový 1
    substrát inzulínový receptorový 2
    substrát inzulínový receptorový 3
    substrát inzulínový receptorový 4
    IRS-1
    IRS-2
    IRS-3
    IRS-4
    Scope note in EnglishA structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR PROTEIN-TYROSINE KINASE. The proteins share an N-terminal PLECKSTRIN HOMOLOGY DOMAIN, a phosphotyrosine-binding domain that interacts with the phosphorylated INSULIN RECEPTOR, and a C-terminal TYROSINE-rich domain. Upon tyrosine phosphorylation, insulin receptor substrate proteins interact with specific SH2 DOMAIN containing proteins that are involved in insulin receptor signaling.
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