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motív inhibičný imunoreceptorový, založený na tyrozíne

  1. Subject h.motív inhibičný imunoreceptorový, založený na tyrozíne
    Subject h.Immunoreceptor Tyrosine-Based Inhibition Motif
    Scope note in EnglishA conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.
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