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hirudíny

  1. Record numberd006629
    Date06.06.2025
    TypeM - MESH
    Topical termhirudíny
    Other termEnglish (Pseudonym) Hirudin
    Slovak (Pseudonym) hirudín
    See also(Skutočné meno) antitrombíny
    (Skutočné meno) fibrinolytiká
    (Later heading) terapia hirudínová
    UDCD12.644.861.060.875D12.776.872.060.875
    NoteSingle-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.
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Number of the records: 1  

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