Number of the records: 1
zidovudín
Record number d015215 Date 12.05.2026 Type M - MESH Topical term zidovudín Other term English (Pseudonym) Azidothymidine
English (Pseudonym) AZT (Antiviral)
English (Pseudonym) Azidothymidine
English (Pseudonym) AZT (Antiviral)
English (Pseudonym) 3'-Azido-2',3'-Dideoxythymidine
English (Pseudonym) 3'-Azido-3'-deoxythymidine
English (Pseudonym) AZT Antiviral
English (Pseudonym) AZT, Antiviral
Slovak (Pseudonym) azidotymidín
Slovak (Pseudonym) AZT (antivírusový)
Slovak (Pseudonym) AZT, antivirotikum
Slovak (Pseudonym) 3'-azido-2',3'-dideoxytimidín
Slovak (Pseudonym) 3'-azido-3'-deoxytimidín
Slovak (Pseudonym) BW A509U
Slovak (Pseudonym) BWA-509U
Slovak (Pseudonym) Retrovir
See also (Skutočné meno) antimetabolity
(Skutočné meno) inhibítory reverznej transkriptázy
(Skutočné meno) látky proti HIV
UDC D03.383.742.680.705.950D13.570.230.500.950D13.570.230.855.950D13.570.685.705.950 Note A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. 
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Number of the records: 1