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modulátory GABA

  1. Record numberd018757
    Date06.06.2025
    TypeM - MESH
    Topical termmodulátory GABA
    Other termEnglish (Pseudonym) gamma-Aminobutyric Acid Modulators
    Slovak (Pseudonym) modulátory kyseliny gama maslovej
    See also(Skutočné meno) hypnotiká a sedatíva
    (Skutočné meno) anxiolytiká
    (Skutočné meno) anestetiká celkové
    (Later heading) GABA transportné proteíny plazmatickej membrány
    UDCD27.505.519.625.240.500D27.505.696.577.240.500
    NoteSubstances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
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