Počet záznamov: 1
Nogo proteíny
Heslo Nogo proteíny Heslo anglicky Nogo Proteins Odkazy retikulon 4-B proteín Vysvetľujúca pozn. v angl. Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system. 
predmetové heslo
Počet záznamov: 1