Počet záznamov: 1
proteíny MutL
Heslo proteíny MutL Heslo anglicky MutL Proteins Odkazy MutL homológy Vysvetľujúca pozn. v angl. DNA repair proteins that include the bacterial MutL protein and its eukaryotic homologs. They consist of a conserved N-terminal region with weak ATPase activity, an endonuclease motif, and a C-terminal domain that forms MutL homodimers or heterodimers between MLH1 and the PMS1, MISMATCH REPAIR ENDONUCLEASE PMS2; or MLH3 proteins. These complexes function in DNA repair pathways, primarily DNA MISMATCH REPAIR, where MutL/MLH1 and the MUTS DNA MISMATCH-BINDING PROTEIN are targeted to damaged DNA. 
predmetové heslo
Počet záznamov: 1