Počet záznamov: 1
proteínkináza C-theta
Heslo proteínkináza C-theta Heslo anglicky Protein Kinase C-theta Odkazy PKC-theta
PRKCQVysvetľujúca pozn. v angl. A calcium-independent, phospholipid- and diacylglycerol-dependent, protein kinase C subtype that contains an N-terminal C2 DOMAIN and two diacylglycerol-binding ZINC FINGERS. It is expressed primarily by T-LYMPHOCYTES and localizes to IMMUNOLOGICAL SYNAPSES where it regulates downstream signaling for the activation, proliferation, and survival of mature T-cells. It plays a critical role in allergic, autoimmune, and alloimmune responses of TH2 CELLS and TH17 CELLS. 
predmetové heslo
Počet záznamov: 1