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MALT-1 proteín
Heslo MALT-1 proteín Heslo anglicky Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein Odkazy parakaspáza
parakaspáza MALT1
proteín lymfómu lymfatického tkaniva asociovaného so sliznicou 1, s translokáciouVysvetľujúca pozn. v angl. A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES. 
predmetové heslo
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