Počet záznamov: 1

etopozid

Heslo	etopozid
Heslo anglicky	Etoposide
Odkazy	Etoposide demetylepipodofylotoxínetylidínglukozid
Angl. X odkazy	Demethyl Epipodophyllotoxin Ethylidine Glucoside
Vysvetľujúca pozn. v angl.	A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
Farmakologický účinok	antineoplastiká fytogénne inhibítory topoizomerázy II
Farmakologický účinok	Antineoplastic Agents, Phytogenic Topoisomerase II Inhibitors
Odkazy	(29) - ČLÁNKY
	(3) - CiBaMed
	(10) - KNIHY

predmetové heslo

Počet záznamov: 1