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glukóza-6-fosfát izomeráza

  1. Hesloglukóza-6-fosfát izomeráza
    Heslo anglickyGlucose-6-Phosphate Isomerase
    Odkazyglukózafosfátizomeráza
    glukóza-6-fosfátizomeráza
    Angl. X odkazyGlucosephosphate Isomerase
    Phosphoglucose Isomerase
    Phosphohexose Isomerase
    Vysvetľujúca pozn. v angl.An aldose-ketose isomerase that catalyzes the reversible interconversion of glucose 6-phosphate and fructose 6-phosphate. In prokaryotic and eukaryotic organisms it plays an essential role in glycolytic and gluconeogenic pathways. In mammalian systems the enzyme is found in the cytoplasm and as a secreted protein. This secreted form of glucose-6-phosphate isomerase has been referred to as autocrine motility factor or neuroleukin, and acts as a cytokine which binds to the AUTOCRINE MOTILITY FACTOR RECEPTOR. Deficiency of the enzyme in humans is an autosomal recessive trait, which results in CONGENITAL NONSPHEROCYTIC HEMOLYTIC ANEMIA.
    Odkazy (2) - ČLÁNKY
    (1) - CiBaMed
    (1) - KNIHY
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