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lichen planus

  1. Subject h.lichen planus
    Subject h.Lichen Planus
    Entry termslichen planus kožný
    lichen planopilaris
    lichen ruber planus
    lichen rubra planus
    lichen planus mukózny
    lichen planus sliznicový
    English X referencesCutaneous Lichen Planus
    Lichen Planopilaris
    Lichen Ruber Planus
    Mucosal Lichen Planus
    Scope note in EnglishAn inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a "saw-tooth" pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.
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