An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs.
Pozri aj (FX) v slov.
anticipácia genetická miesta chromozómov fragilné fragilita chromozómov syndróm fragilného chromozómu X dystrofia myotonická
